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Article

Molecular variability elicits a tunable switch with discrete neuromodulatory response phenotypes.

Journal of computational neuroscience - 1 Feb 2016

Anderson Warren D, Makadia Hirenkumar K, Vadigepalli Rajanikanth

Abstract excerpt

Recent single cell studies show extensive molecular variability underlying cellular responses. We evaluated the impact of molecular variability in the expression of cell signaling components and ion channels on electrophysiological excitability and neuromodulation. We employed a computational approach that integrated neuropeptide receptor-mediated signaling with electrophysiology. We simulated a population of...

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Identifiers

PMID: 26621106
DOI: 10.1007/s10827-015-0584-2
PMCID: PMC4867553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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