Article
Centrosomes and the Scrambled protein coordinate microtubule-independent actin reorganization.
Nature cell biology - 1 Jan 2001
Stevenson V A, Kramer J, Kuhn J, Theurkauf W E
Abstract excerpt
In Drosophila syncytial blastoderm embryos, centrosomes specify the position of actin-based interphase caps and mitotic furrows. Mutations in the scrambled locus prevent assembly of mitotic furrows, but do not block actin cap formation. The scrambled gene encodes a protein that localizes to the mitotic furrows and centrosomes. Sced localization, actin reorganization from caps into mitotic furrows, and...
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