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Article

Investigating NF-κB signaling in lung fibroblasts in 2D and 3D culture systems

30 Nov 2015

Abstract excerpt

BACKGROUND: Inflammatory respiratory diseases are amongst major global health challenges. Lung fibroblasts have been shown to play a key role in lung inflammatory responses. However, their exact role in initiation and maintenance of lung diseases has remained elusive partly due to the limited availability of physiologically relevant in vitro models. Therefore, developing new tools that enable investigating the...

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PMID: 26619903
DOI: 10.1186/s12931-015-0302-7

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