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Constructing a 3D co-culture in vitro synovial tissue model for rheumatoid arthritis research

24 Jan 2025

Abstract excerpt

The development and exploration of highly effective drugs for rheumatoid arthritis remains an urgent necessity. However, current disease research models are no longer sufficient to meet the rapid development of high-throughput drug screening. In this study, bacterial cellulose simulating the structure of extracellular matrix was used as a 3D culture platform, and THP-1-derived M1 macrophages, representing the...

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PMID: 39968522
DOI: 10.1016/j.mtbio.2025.101492

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