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Article

Down-regulation of TET2 in CD3⁺ and CD34⁺ cells of myelodysplastic syndromes and enhances CD34⁺ cells proliferation.

International journal of clinical and experimental pathology - 1 Jan 2015

Zhang Wei, Shao Zonghong, Fu Rong, Wang Huaquan, Li Lijuan, Liu Hui

Abstract excerpt

AIMS AND BACKGROUND: To investigate the expressions of TET2 mRNA in bone marrow CD3(+) and CD34(+) cells of the patients with myelodysplastic syndromes (MDS) and to study the effect of silencing TET2 by small interfering RNA (siRNA) on the biological characteristics of CD34(+) cells. METHODS: CD3(+) and CD34(+) cells were sorted by magnetic activated cell-sorting system from bone marrow of MDS patients and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26617797
PMCID: PMC4637612

Genes

TET2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Down-regulation of TET2 in CD3⁺ and CD34⁺ cells of myelodysplastic syndromes and enhances CD34⁺ cells proliferation.PMID 26617797Read ↗

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