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Article

Using measures of single-cell physiology and physiological state to understand organismic aging.

Aging cell - 1 Feb 2016

Mendenhall Alexander, Driscoll Monica, Brent Roger

Abstract excerpt

Genetically identical organisms in homogeneous environments have different lifespans and healthspans. These differences are often attributed to stochastic events, such as mutations and 'epimutations', changes in DNA methylation and chromatin that change gene function and expression. But work in the last 10 years has revealed differences in lifespan- and health-related phenotypes that are not caused by lasting...

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PMID: 26616110
DOI: 10.1111/acel.12424
PMCID: PMC4717262

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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