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Systems biology of aging.

Advances in experimental medicine and biology - 1 Jan 2015

Bolt Kendra, Bergman Aviv

Abstract excerpt

Human aging occurs at rates that vary widely between organisms and cell types. We hypothesize that in both cases, variation is due to differences in heat production, heat management and molecular susceptibility to heat-induced change. Metabolic rates have long been implored for their contributions to the aging process, with a negative correlation observed between basal metabolic rate and lifespan (Savage et al.,...

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PMID: 25916591
DOI: 10.1007/978-1-4939-2404-2_8

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