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Article

Genetic association with ERAP1 in psoriasis is confined to disease onset after puberty and not dependent on HLA-C*06.

The Journal of investigative dermatology - 1 Feb 2013

Lysell Josefin, Padyukov Leonid, Kockum Ingrid, Nikamo Pernilla, Ståhle Mona

Abstract excerpt

HLA-C remains the strongest susceptibility candidate gene in psoriasis. Evidence for interaction between HLA-C and endoplasmic reticulum aminopeptidase 1 (ERAP1) confined to individuals carrying the HLA-C risk allele was recently reported. Psoriasis displays wide variation, and genetic heterogeneity is likely to contribute to clinical diversity. Age at disease onset is a putative discriminator, and separating...

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Source

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Identifiers

PMID: 22931917
DOI: 10.1038/jid.2012.280
PMCID: PMC3547223

Genes

ERAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic association with ERAP1 in psoriasis is confined to disease onset after puberty and not dependent on HLA-C*06.PMID 22931917Read ↗

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