Article
Expanded endothelial progenitor cells mitigate lung injury in septic mice.
Stem cell research & therapy - 26 Nov 2015
Güldner Andreas, Maron-Gutierrez Tatiana, Abreu Soraia Carvalho, Xisto Debora Gonçalves, Senegaglia Alexandra Cristina, Barcelos Patty Rose da Silva, Silva Johnatas Dutra, Brofman Paulo, de Abreu Marcelo Gama, Rocco Patricia Rieken Macedo
Abstract excerpt
Endothelial progenitor cells (EPCs) improve survival and reduce organ failure in cecal ligation and puncture-induced sepsis; however, expanded EPCs may represent an even better approach for vascular repair. To date, no study has compared the effects of non-expanded EPCs (EPC-NEXP) with those of expanded EPCs (EPC-EXP) and mesenchymal stromal cells of human (MSC-HUMAN) and mouse (MSC-MICE) origin in experimental...
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