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Article

The expression of functional Toll-like receptor 4 is associated with proliferation and maintenance of stem cell phenotype in endothelial progenitor cells (EPCs).

Journal of cellular biochemistry - 1 Sept 2010

He Jin, Xiao Zhilin, Chen Xiaobin, Chen Meifang, Fang Li, Yang Mei, Lv Qingshan, Li Yuehui, Li Guancheng, Hu Jinyue, Xie Xiumei

Abstract excerpt

Endothelial dysfunction is involved in various cardiovascular diseases such as atherosclerosis. Endothelial progenitor cells (EPCs) contribute to re-endothelialization and neo-vascularization, and the increase of EPCs in peripherial circulation benefits the prognosis of cardiovascular disease. However, little is known about the biological stimuli that initiate the proliferation and the maintenance of stem cell...

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Source

Identifiers

PMID: 20506307
DOI: 10.1002/jcb.22686

Genes

TLR4
TLR2
TLR8
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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