Article
Darier's disease: from dyskeratosis to endoplasmic reticulum calcium ATPase deficiency.
Biochemical and biophysical research communications - 1 Oct 2004
Hovnanian Alain
Abstract excerpt
The skin is the body's largest organ and has an essential barrier protective function against physical, chemical, and pathogen aggressions and prevents fluid loss. The outer layer of the skin, known as the epidermis, plays a key role in this protection, through a tightly regulated differentiation programme from basal keratinocytes to the stratum corneum at the skin surface. During this process, keratinocytes from...
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