Article
Regulatory network reconstruction reveals genes with prognostic value for chronic lymphocytic leukemia.
BMC genomics - 25 Nov 2015
Yepes Sally, Torres Maria Mercedes, López-Kleine Liliana
Abstract excerpt
BACKGROUND: The clinical course of chronic lymphocytic leukemia (CLL) is highly variable; some patients follow an indolent course, but others progress to a more advanced stage. The mutational status of rearranged immunoglobulin heavy chain variable (IGVH) genes in CLL is a feature that is widely recognized for dividing patients into groups that are related to their prognoses. However, the regulatory programs...
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