Article
Transcriptional master regulator analysis in breast cancer genetic networks.
Computational biology and chemistry - 1 Dec 2015
Tovar Hugo, García-Herrera Rodrigo, Espinal-Enríquez Jesús, Hernández-Lemus Enrique
Abstract excerpt
Gene regulatory networks account for the delicate mechanisms that control gene expression. Under certain circumstances, gene regulatory programs may give rise to amplification cascades. Such transcriptional cascades are events in which activation of key-responsive transcription factors called master regulators trigger a series of gene expression events. The action of transcriptional master regulators is then...
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