Article
Genomic Copy Number Alterations in Renal Cell Carcinoma with Sarcomatoid Features.
The Journal of urology - 1 Apr 2016
Ito Timothy, Pei Jianming, Dulaimi Essel, Menges Craig, Abbosh Philip H, Smaldone Marc C, Chen David Y T, Greenberg Richard E, Kutikov Alexander, Viterbo Rosalia, Uzzo Robert G, Testa Joseph R
Abstract excerpt
PURPOSE: Sarcomatoid changes in renal cell carcinoma are associated with a poor prognosis. The identification of genetic alterations that drive this aggressive phenotype could aid in the development of more effective targeted therapies. In this study we aimed to pinpoint unique copy number alterations in sarcomatoid renal cell carcinoma compared to classical renal cell carcinoma subtypes. MATERIALS AND METHODS:...
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