Article
BRAF V600K vs. BRAF V600E: a comparison of clinical and dermoscopic characteristics and response to immunotherapies and targeted therapies.
Clinical and experimental dermatology - 1 Jun 2022
Zengarini Corrado, Mussi Martina, Veronesi Giulia, Alessandrini Aurora, Lambertini Martina, Dika Emi
Abstract excerpt
BACKGROUND: A number of mutations related to malignant melanoma (MM) have been identified, and of the mutated genes, BRAF has been found to be altered in > 50% of cases. Most of these have been BRAF V600E mutations, whereas the incidence of BRAF V600K may vary from 10% to 30%. Little is known about the clinical prognostic correlations of BRAF V600K MMs. We evaluated the clinical and dermoscopic features,...
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