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Article

GWAS as a Driver of Gene Discovery in Cardiometabolic Diseases.

Trends in endocrinology and metabolism: TEM - 1 Dec 2015

Atanasovska Biljana, Kumar Vinod, Fu Jingyuan, Wijmenga Cisca, Hofker Marten H

Abstract excerpt

Cardiometabolic diseases represent a common complex disorder with a strong genetic component. Currently, genome-wide association studies (GWAS) have yielded some 755 single-nucleotide polymorphisms (SNPs) encompassing 366 independent loci that may help to decipher the molecular basis of cardiometabolic diseases. Going from a disease SNP to the underlying disease mechanisms is a huge challenge because the...

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PMID: 26596674
DOI: 10.1016/j.tem.2015.10.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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