Article
Genetic determinants of cardiometabolic risk: a proposed model for phenotype association and interaction.
Journal of clinical lipidology - 1 Jan 2000
Blackett Piers R, Sanghera Dharambir K
Abstract excerpt
This review provides a translational and unifying summary of metabolic syndrome genetics and highlights evidence that genetic studies are starting to unravel and untangle origins of the complex and challenging cluster of disease phenotypes. The associated genes effectively express in the brain, liver, kidney, arterial endothelium, adipocytes, myocytes, and β cells. Progression of syndrome traits has been...
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