Article
Mitochondrial D-loop Variations in Infertile Women Undergoing in Vitro Fertilization-Embryo Transfer.
The Journal of reproductive medicine - 1 Jan 2000
Lin Yue, Chen Yizuo, Du Jing, Huang Xuefeng, Zhao Junzhao, Sun Xiaoxi
Abstract excerpt
OBJECTIVE: To show a high frequency of human mitochondrial DNA (mtDNA) D-loop variations present in infertile women undergoing in vitro fertilization-embryo transfer (IVF-ET) and the variation's potential relevance as a predictive marker in the IVF-ET. STUDY DESIGN: The entire mtDNA D-loop region was amplified in 3 overlapping polymerase chain reaction fragments, and the variations were evaluated through direct...
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