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Article

Comprehensive mitochondrial DNA analysis and IVF outcome

1 Jan 2018

Abstract excerpt

STUDY QUESTION: Do mitochondrial DNA (mtDNA) copy number and heteroplasmy in human embryos affect the ongoing pregnancy rate? SUMMARY ANSWER: Our study suggests that mtDNA copy number above a specific threshold is associated with the ongoing pregnancy rate. WHAT IS KNOWN ALREADY: Mitochondria play a vital role in cell function. Recently, there has been increasing research on mtDNA as a biomarker of embryo...

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Identifiers

PMID: 30895263
DOI: 10.1093/hropen/hoy023

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