Article
Mitochondrial D-loop variations in infertile women undergoing a long stimulation protocol.
European journal of obstetrics, gynecology, and reproductive biology - 1 Feb 2012
Lin Yue, Du Jing, Li Lu, Fu Jing, Wang Min, Zhang Zhaofeng, Sun Xiaoxi
Abstract excerpt
OBJECTIVE: To study a high frequency of mtDNA D-loop variations in infertile women undergoing a long stimulation protocol and their potential relevance with endpoints of IVF. STUDY DESIGN: Peripheral blood was taken from 156 patient ≤ 42 years of age. The entire D-loop region of mtDNA was amplified in three overlapping polymerase chain reaction fragments, and variations were evaluated by direct DNA sequencing...
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