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Article

C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation.

Nature communications - 20 Nov 2015

Hahm Jeong-Hoon, Kim Sunhee, DiLoreto Race, Shi Cheng, Lee Seung-Jae V, Murphy Coleen T, Nam Hong Gil

Abstract excerpt

Ageing is marked by physical decline. Caenorhabditis elegans is a valuable model for identifying genetic regulatory mechanisms of ageing and longevity. Here we report a simple method to assess C. elegans' maximum physical ability based on the worms' maximum movement velocity. We show maximum velocity declines with age, correlates well with longevity, accurately reports movement ability and, if measured in...

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Identifiers

PMID: 26586186
DOI: 10.1038/ncomms9919
PMCID: PMC4656132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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