Article
Circulating tumor DNA identified by targeted sequencing in advanced-stage non-small cell lung cancer patients.
Cancer letters - 28 Jan 2016
Xu Song, Lou Feng, Wu Yi, Sun Da-Qiang, Zhang Jing-Bo, Chen Wei, Ye Hua, Liu Jing-Hao, Wei Sen, Zhao Ming-Yu, Wu Wen-Jun, Su Xue-Xia, Shi Rong, Jones Lindsey, Huang Xue F, Chen Si-Yi, Chen Jun
Abstract excerpt
Non-small cell lung cancers (NSCLC) have unique mutation patterns, and some of these mutations may be used to predict prognosis or guide patient treatment. Mutation profiling before and during treatment often requires repeated tumor biopsies, which is not always possible. Recently, cell-free, circulating tumor DNA (ctDNA) isolated from blood plasma has been shown to contain genetic mutations representative of...
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