Article
Circulating Tumor DNA Detection in Early-Stage Non-Small Cell Lung Cancer Patients by Targeted Sequencing.
Scientific reports - 24 Aug 2016
Chen Ke-Zhong, Lou Feng, Yang Fan, Zhang Jing-Bo, Ye Hua, Chen Wei, Guan Tian, Zhao Ming-Yu, Su Xue-Xia, Shi Rong, Jones Lindsey, Huang Xue F, Chen Si-Yi, Wang Jun
Abstract excerpt
Circulating tumor DNA (ctDNA) isolated from peripheral blood has recently been shown to be an alternative source to detect gene mutations in primary tumors; however, most previous studies have focused on advanced stage cancers, and few have evaluated ctDNA detection in early-stage lung cancer. In the present study, blood and tumor samples were collected prospectively from 58 early-stage non-small lung cancer...
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