Article
Detection of cancer specific mutations in early-stage non-small cell lung cancer using cell-free DNA by targeted sequencing.
International journal of oncology - 1 Dec 2016
He Yutong, Zhang Xinyuan, Wang Liqun, Tian Ziqiang, Liu Qingyi, Yao Jifang, Liu Yueping, Li Chuanbao, Min Li, Shan Baoen
Abstract excerpt
Non-small cell lung cancer (NSCLC) is a major public health problem worldwide and leads to a high mortality. NSCLC is always diagnosed in late stages because of its unapparent symptoms. However, cell-free DNA (cfDNA) may serve as a new potential biomarker to detect early stage of non‑small cell lung cancer. Here we recruited 10 non-small cell lung cancer patients to obtain fresh tumor tissue, peripheral blood...
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