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Article

Clinical Utility of Circulating Tumor DNA for Detecting Lung Cancer Mutations by Targeted Next-Generation Sequencing With Insufficient Tumor Samples.

Journal of clinical laboratory analysis - 1 Oct 2024

Sun Yi, Zhang Xu, Yang Xinhua, Ma Jiangjun

Abstract excerpt

BACKGROUND: Circulating tumor deoxyribonucleic acid (ctDNA) is increasingly applied in clinical practice. This study aimed to explore clinical utility of a minimal invasive and sensitive way of ctDNA for next-generation sequencing in non-small cell lung cancer (NSCLC) with inadequate tumor samples. METHODS: Targeted DNA sequencing was performed on tissue biopsies and matched plasma samples from 60 patients with...

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Source

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Identifiers

PMID: 39315762
DOI: 10.1002/jcla.25099
PMCID: PMC11520943

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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