Article
Cohort of estrogen-induced microRNAs regulate adrenomedullin expression.
American journal of physiology. Regulatory, integrative and comparative physiology - 15 Jan 2016
Wetzel-Strong Sarah E, Li Manyu, Espenschied Scott T, Caron Kathleen M
Abstract excerpt
Estrogen regulates the expression of many genes and has been correlated with differences in cardiac contraction; however, the underlying mechanisms remain poorly defined. Adrenomedullin (Adm = gene; AM = protein) is a multifunctional peptide with inotropic actions. Previous studies have demonstrated that estrogen enhances the expression of Adm, suggesting a relationship between AM and estrogen in cardiac...
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