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Article

Sexual dimorphisms of mRNA and miRNA in human/murine heart disease

13 Jul 2017

Abstract excerpt

BACKGROUND: Sexual dimorphisms are well recognized in various cardiac diseases such as ischemic cardiomyopathy (ICM), hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM). Thorough understanding of the underlying genetic programs is crucial to optimize treatment strategies specified for each gender. By performing meta-analysis and microarray analysis, we sought to comprehensively characterize the...

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PMID: 28704447
DOI: 10.1371/journal.pone.0177988

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