Article
Endogenous hepatic glucocorticoid receptor signaling coordinates sex‐biased inflammatory gene expression
18 Nov 2015
Abstract excerpt
An individual's sex affects gene expression and many inflammatory diseases present in a sex-biased manner. Glucocorticoid receptors (GRs) are regulators of inflammatory genes, but their role in sex-specific responses is unclear. Our goal was to evaluate whether GR differentially regulates inflammatory gene expression in male and female mouse liver. Twenty-five percent of the 251 genes assayed by nanostring...
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