Article
Sex differences in resident immune cell phenotype underlie more efficient acute inflammatory responses in female mice.
Blood - 24 Nov 2011
Scotland Ramona S, Stables Melanie J, Madalli Shimona, Watson Peter, Gilroy Derek W
Abstract excerpt
Females are protected against mortality arising from severe sepsis; however, the precise mechanisms that confer this survival advantage in females over males are unclear. Resident leukocytes in resting tissues have a significant influence on circulating cytokine levels and recruitment of blood leukocytes during acute inflammatory responses. Whether the phenotype of resident leukocytes is distinct in females is...
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