Article
Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis
29 May 2007
Abstract excerpt
Sexual dimorphism in mammalian liver impacts genes affecting hepatic physiology, including inflammatory responses, diseased states, and the metabolism of steroids and foreign compounds. Liver sex specificity is dictated by sex differences in pituitary growth hormone (GH) secretion, with the transcription factor signal transducer and activator of transcription (STAT)5b required for intracellular signaling...
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