Article
Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma.
World journal of gastroenterology - 14 Nov 2015
Chiu Amy P, Tschida Barbara R, Lo Lilian H, Moriarity Branden S, Rowlands Dewi K, Largaespada David A, Keng Vincent W
Abstract excerpt
The major type of human liver cancer is hepatocellular carcinoma (HCC), and there are currently many risk factors that contribute to this deadly disease. The majority of HCC occurrences are associated with chronic hepatitis viral infection, and hepatitis B viral (HBV) infection is currently a major health problem in Eastern Asia. Elucidating the genetic mechanisms associated with HBV-induced HCC has been...
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