Article
Zebrafish as a disease model for studying human hepatocellular carcinoma.
World journal of gastroenterology - 14 Nov 2015
Lu Jeng-Wei, Ho Yi-Jung, Yang Yi-Ju, Liao Heng-An, Ciou Shih-Ci, Lin Liang-In, Ou Da-Liang
Abstract excerpt
Liver cancer is one of the world's most common cancers and the second leading cause of cancer deaths. Hepatocellular carcinoma (HCC), a primary hepatic cancer, accounts for 90%-95% of liver cancer cases. The pathogenesis of HCC consists of a stepwise process of liver damage that extends over decades, due to hepatitis, fatty liver, fibrosis, and cirrhosis before developing fully into HCC. Multiple risk factors are...
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