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Article

ALDH1A3: A Marker of Mesenchymal Phenotype in Gliomas Associated with Cell Invasion.

PloS one - 1 Jan 2015

Zhang Wenlong, Liu Yanwei, Hu Huimin, Huang Hua, Bao Zhaoshi, Yang Pei, Wang Yinyan, You Gan, Yan Wei, Jiang Tao, Wang Jiangfei, Zhang Wei

Abstract excerpt

Aldehyde dehydrogenases (ALDH) is a family of enzymes including 19 members. For now, ALDH activity had been wildly used as a marker of cancer stem cells (CSCs). But biological functions of relevant isoforms and their clinical applications are still controversial. Here, we investigate the clinical significance and potential function of ALDH1A3 in gliomas. By whole-genome transcriptome microarray and mRNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26575197
DOI: 10.1371/journal.pone.0142856
PMCID: PMC4648511

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ALDH1A3: A Marker of Mesenchymal Phenotype in Gliomas Associated with Cell Invasion.PMID 26575197Read ↗

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