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Article

Malignant clinical features of anaplastic gliomas without IDH mutation.

Neuro-oncology - 1 Jan 2015

Shibahara Ichiyo, Sonoda Yukihiko, Shoji Takuhiro, Kanamori Masayuki, Saito Ryuta, Inoue Tomoo, Kawaguchi Tomohiro, Yamashita Yoji, Watanabe Takashi, Kumabe Toshihiro, Watanabe Mika, Suzuki Hiroyoshi, Tominaga Teiji

Abstract excerpt

BACKGROUND: Diagnosis of WHO grade III anaplastic gliomas does not always correspond to its clinical outcome because of the isocitrate dehydrogenase (IDH) gene status. Anaplastic gliomas without IDH mutation result in a poor prognosis, similar to grade IV glioblastomas. However, the malignant features of anaplastic gliomas without IDH mutation are not well understood. The aim of this study was to examine...

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Identifiers

PMID: 24958096
DOI: 10.1093/neuonc/nou112
PMCID: PMC4483044

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SOX2
MGMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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