Article
Association between single nucleotide polymorphisms of the G-protein γ5 subunit and the risk of essential hypertension in the population of Poland.
Polskie Archiwum Medycyny Wewnetrznej - 1 Jan 2015
Hejduk Paulina, Sakowicz Agata M, Mikołajczyk Melania, Śliwińska Agnieszka, Drzewoski Józef, Pietrucha Tadeusz
Abstract excerpt
INTRODUCTION: Polymorphisms in genes coding G-protein subunits (α, β, and γ) may affect the response of stimulated α2A-adrenergic receptors, which are involved in the regulation of blood pressure. OBJECTIVES The aim of the present study was to determine the association between the rs11559300 (A/G), rs199705300 (C/A), rs61754630 (C/T), rs13093 (C/A), and rs41284589 (C/T) single nucleotide polymorphisms (SNPs) of...