Article
Association of peroxisome proliferator-activated receptor γ polymorphisms and haplotypes with essential hypertension.
Genetic testing and molecular biomarkers - 1 May 2013
Gu Shu-Jun, Guo Zhi-Rong, Wu Ming, Ding Yi, Luo Wen-Shu
Abstract excerpt
Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor involved in the regulation of several biochemical pathways. Blood pressure-lowering effects have been found in PPARγ agonists in several hypertensive models. The biology and research data related to the gene suggest that it could play a role in essential hypertension (EH) susceptibility. This study aimed to investigate the association...
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