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Article

Neuropilins: A New Target for Cancer Therapy

8 Apr 2011

Abstract excerpt

Recent investigations highlighted strong similarities between neural crest migration during embryogenesis and metastatic processes. Indeed, some families of axon guidance molecules were also reported to participate in cancer invasion: plexins/semaphorins/neuropilins, ephrins/Eph receptors, netrin/DCC/UNC5. Neuropilins (NRPs) are transmembrane non tyrosine-kinase glycoproteins first identified as receptors for...

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PMID: 24212788
DOI: 10.3390/cancers3021899

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