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Article

High-throughput mRNA and miRNA profiling of epithelial-mesenchymal transition in MDCK cells

16 Nov 2015

Abstract excerpt

BACKGROUND: Epithelial-mesenchymal transition (EMT) is an important process in embryonic development, especially during gastrulation and organ formation. Furthermore EMT is widely observed in pathological conditions, e.g., fibrosis, tumor progression and metastasis. Madin-Darby Canine Kidney (MDCK) cells are widely used for studies of EMT and epithelial plasticity. MDCK cells show an epithelial phenotype, while...

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PMID: 26572553
DOI: 10.1186/s12864-015-2036-9

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