Article
Analysis of microRNA expression in canine mammary cancer stem-like cells indicates epigenetic regulation of transforming growth factor-beta signaling.
Journal of physiology and pharmacology : an official journal of the Polish Physiological Society - 1 Feb 2015
Rybicka A, Mucha J, Majchrzak K, Taciak B, Hellmen E, Motyl T, Krol M
Abstract excerpt
Cancer stem cells (CSCs) display both unique self-renewal ability as well as the ability to differentiate into many kinds of cancer cells. They are supposed to be responsible for cancer initiation, recurrence and drug resistance. Despite the fact that a variety of methods are currently employed in order to target CSCs, little is known about the regulation of their phenotype and biology by miRNAs. The aim of our...
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