Article
Microarray-based approach identifies microRNAs and their target functional patterns in polycystic kidney disease
1 Dec 2008
Abstract excerpt
BACKGROUND: MicroRNAs (miRNAs) play key roles in mammalian gene expression and several cellular processes, including differentiation, development, apoptosis and cancer pathomechanisms. Recently the biological importance of primary cilia has been recognized in a number of human genetic diseases. Numerous disorders are related to cilia dysfunction, including polycystic kidney disease (PKD). Although involvement of...
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