Article
Truncated RASSF7 promotes centrosomal defects and cell death.
Developmental biology - 15 Jan 2016
Gulsen Tulay, Hadjicosti Irene, Li Yueshi, Zhang Xinyun, Whitley Paul R, Chalmers Andrew D
Abstract excerpt
RASSF7 protein localises to the centrosome and plays a key role in mitosis. Its expression is also increased in a range of tumour types. However, little is known about the molecular basis of RASSF7's function and it is not clear if it acts as an oncogene in the cancers where its levels are elevated. Here, we carry out the first analysis of the domains of rassf7, focusing on which of them are responsible for its...
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