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Article

MR-PheWAS: hypothesis prioritization among potential causal effects of body mass index on many outcomes, using Mendelian randomization.

Scientific reports - 16 Nov 2015

Millard Louise A C, Davies Neil M, Timpson Nic J, Tilling Kate, Flach Peter A, Davey Smith George

Abstract excerpt

Observational cohort studies can provide rich datasets with a diverse range of phenotypic variables. However, hypothesis-driven epidemiological analyses by definition only test particular hypotheses chosen by researchers. Furthermore, observational analyses may not provide robust evidence of causality, as they are susceptible to confounding, reverse causation and measurement error. Using body mass index (BMI) as...

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PMID: 26568383
DOI: 10.1038/srep16645
PMCID: PMC4644974

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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