Article
Dynamic interplay of multidrug transporters with TolC for isoprenol tolerance in Escherichia coli.
Scientific reports - 13 Nov 2015
Wang Chonglong, Yang Liyang, Shah Asad Ali, Choi Eui-Sung, Kim Seon-Won
Abstract excerpt
Engineering of efflux pumps is a promising way to improve host's tolerance to biofuels such as medium-chain alcohols (CmOHs); however, this strategy is restricted by poor understanding of the efflux pumps engaged in extrusion of solvents. In this study, several Escherichia coli mutants of multidrug transporters were evaluated for isoprenol tolerance. Susceptible phenotypes were observed in the mutants with...
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