Article
Improvement in organic solvent tolerance by double disruptions of proV and marR genes in Escherichia coli.
Journal of applied microbiology - 1 Mar 2012
Doukyu N, Ishikawa K, Watanabe R, Ogino H
Abstract excerpt
AIMS: To investigate the involvement of osmoprotectant transporters in organic solvent tolerance in Escherichia coli and to construct an E. coli strain with high organic solvent tolerance. METHODS AND RESULTS: The organic solvent tolerance of ΔbetT, ΔproV, ΔproP or ΔputP single-gene knockout mutants of E. coli K-12 strain was examined. Among these mutants, the organic solvent tolerance of the ΔproV mutant...
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