Article
Predicting DNA mutations during cancer evolution.
International journal of bioinformatics research and applications - 1 Jan 2015
Martinez Juan Carlos, Lopez-Jimenez Nelson, Meng Tao, Iyengar S S
Abstract excerpt
Bio-systems are inherently complex information processing systems. Their physiological complexities limit the formulation and testing of a hypothesis for their behaviour. Our goal here was to test a computational framework utilising published data from a longitudinal study of patients with acute myeloid leukaemia (AML), whose DNA from both normal and malignant tissues were subjected to NGS analysis at various...
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