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Article

Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnostics.

International journal of molecular sciences - 30 May 2014

Kucukkal Tugba G, Yang Ye, Chapman Susan C, Cao Weiguo, Alexov Emil

Abstract excerpt

DNA mutations are the cause of many human diseases and they are the reason for natural differences among individuals by affecting the structure, function, interactions, and other properties of DNA and expressed proteins. The ability to predict whether a given mutation is disease-causing or harmless is of great importance for the early detection of patients with a high risk of developing a particular disease and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 24886813
DOI: 10.3390/ijms15069670
PMCID: PMC4100115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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