Article
Analysis of HLA-B15 and HLA-B27 in spondyloarthritis with peripheral and axial clinical patterns.
BMJ open - 11 Nov 2015
Londono John, Santos Ana Maria, Peña Paola, Calvo Enrique, Espinosa Luis R, Reveille John D, Vargas-Alarcon Gilberto, Jaramillo Carlos A, Valle-Oñate Rafael, Avila Mabel, Romero Consuelo, Medina Juan F
Abstract excerpt
OBJECTIVE: Human leucocyte antigen (HLA) B27 and HLA-B15 are associated with spondyloarthritis (SpA). Recent Assessment of SpondyloArthritis international Society (ASAS) criteria emphasise a distinction between SpA with axial and peripheral patterns. We analysed whether HLA-A, HLA-B and HLA-DRB1 alleles could associate with these patterns. METHODS: We studied 100 healthy individuals and 178 patients with SpA...
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