Article
Familial and genetic aspects of spondyloarthropathy.
Rheumatic diseases clinics of North America - 1 Aug 2003
Breban Maxime, Said-Nahal Roula, Hugot Jean-Pierre, Miceli-Richard Corinne
Abstract excerpt
Predisposition to SpA is largely determined by genetic factors including HLA-B27 and other as yet unknown genes that might be tracked by a positional cloning approach. Analysis performed on a large cohort of SpA multiplex families revealed that the different articular and extra-articular inflammatory manifestations comprising the SpA spectrum were linked together, implying that they were determined by a shared...
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