Article
LPL is the strongest prognostic factor in a comparative analysis of RNA-based markers in early chronic lymphocytic leukemia.
Haematologica - 1 Aug 2011
Kaderi Mohd Arifin, Kanduri Meena, Buhl Anne Mette, Sevov Marie, Cahill Nicola, Gunnarsson Rebeqa, Jansson Mattias, Smedby Karin Ekström, Hjalgrim Henrik, Jurlander Jesper, Juliusson Gunnar, Mansouri Larry, Rosenquist Richard
Abstract excerpt
BACKGROUND: The expression levels of LPL, ZAP70, TCL1A, CLLU1 and MCL1 have recently been proposed as prognostic factors in chronic lymphocytic leukemia. However, few studies have systematically compared these different RNA-based markers. DESIGN AND METHODS: Using real-time quantitative PCR, we measured the mRNA expression levels of these genes in unsorted samples from 252 newly diagnosed chronic lymphocytic...
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