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Article

Natural Guided Genome Engineering Reveals Transcriptional Regulators Controlling Quorum-Sensing Signal Degradation.

PloS one - 1 Jan 2015

El Sahili Abbas, Kwasiborski Anthony, Mothe Nicolas, Velours Christophe, Legrand Pierre, Moréra Solange, Faure Denis

Abstract excerpt

Quorum-quenching (QQ) are natural or engineered processes disrupting the quorum-sensing (QS) signalling which controls virulence and persistence (e.g. biofilm) in numerous bacteria. QQ involves different enzymes including lactonases, amidases, oxidases and reductases which degrade the QS molecules such as N-acylhomoserine lactones (NAHL). Rhodococcus erythropolis known to efficiently degrade NAHL is proposed as a...

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Identifiers

PMID: 26554837
DOI: 10.1371/journal.pone.0141718
PMCID: PMC4640858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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